The culmination of over 150 years of Japanese skincare innovation. Discover 3 visible changes in 3 days: radiance, resilience, and smoothness*. Ultimune face serum is powered by collagen-supporting peptides as well as nourishing and smoothing antioxidants to strengthen skins protective barrier, leaving it smoother and plumper. Smooth fine lines in just 4 weeks** with Ultimune Power Infusing Serum. *Consumer tested by 103 women. **Consumer tested by 90 individuals. TEST RESULTS In 3 days, skin is more radiant, resilient, and smooth* In 4 weeks, fine lines are smoothed** *Consumer tested by 103 women. **Consumer tested by 90 individuals. HOW TO USE Use Ultimune after cleansing and softening skin, but before applying any other serums or moisturizers. Pump twice onto your fingertips and smooth evenly over face and neck. Use Ultimune twice daily, morning and night. KEY INGREDIENTS Fermented Roselle Extract: Increases skins capacity to hold water and is known to support elastin for plumper, smoother, and more radiant skin. Heartleaf Extract: An Eastern ancient herb that helps to soothe skin and helps strengthen its protective barrier. It is known to optimize oxygenation for skin resilience. Reishi Mushroom: Rich in antioxidants and polysaccharides, it hydrates skin to visibly reduce signs of aging. Iris Root Extract: Known to survive in extreme temperatures, this hardy plant is recognized for its vitality and moisturizing abilities. Hydroxyproline: A collagen-supporting peptide known to reduce visible lines and wrinkles.